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 Asthma + Hayfever: BreatheClearInnovative Natural Asthma Solution Produces Excellent Results for Many Sufferers
What BreatheClear can do for youBreatheClear is an innovative nutraceutical that is, for many, providing significant natural relief from the symptoms of asthma and hayfever. Initial research shows that some users with quite severe symptoms have been able to reduce or even discontinue other treatments: when BreatheClear does work, the results can be remarkable. (Of course you MUST work with your doctor if you're going to try this!) But for reasons that are still being investigated, around 50% of users are getting excellent results while the other 50% are getting no benefit: it seems to be all or nothing. It's early days for this product, and we're still unable to predict who will respond and who won't. But the results can be so good when it does work that we want to offer you the opportunity to try it at our risk, with an unconditional 60 day money-back guarantee. So if you suffer from asthma or hayfever you have nothing to loose from reading on... A synergy of two powerful nutraceutical ingredientsBreatheClear contains two clinically proven nutraceutical ingredients: NT Factor and Quercetin. NT Factor reduces the vulnerability of your airways to oxidative attackNT Factor is the only known substance that can actually reverse oxidative damage to the cells by repairing damaged lipids in the cell membranes: a process known as Lipid Replacement Therapy. This is important for asthma sufferers, as it is becoming increasingly recognised that oxidation damage plays a significant role in the pathogenesis of airway inflammation. Because they come into direct contact with external pollutants, the airways are vulnerable to many kinds of oxidative attack. Uniquely, NT Factor can help "armour" your airways against oxidation damage, which could reduce your vulnerability to inflammation. NT Factor enhances the anti-inflammatory & anti-oxidant activity of QuercetinBecause of its action on the cell membranes, when NT Factor is used as a binding agent for other ingredients they become more bioavailable and their effects are often greatly enhanced. A flavonoid derived from apples, Quercetin is a proven anti-histamine, anti-inflammatory and antioxidant. There is research demonstrating its value in the treatment of asthma, though taken on its own the effect is relatively modest. But when bound with NT Factor, it appears that for many sufferers the action of the Quercetin is strengthened - sometimes, as we have said, with spectacular results. BreatheClear also contains amino acids designed to support the action of the NT Factor and Quercetin. Natural, safe and free from side effectsWhile Corticosteroid treatment has been a godsend for asthma sufferers, the side effects can be a concern. As nutraceuticals derived from food, NT Factor and Quercetin are both regarded as safe. There are no reported side-effects from BreatheClear. If you are fortunate to be one of the 50% who does respond, the long-term safety of BreatheClear offers obvious advantages if it enables you to reduce, or even eliminate your drug-based treatment. Though we repeat again: if you do give this a try, it is vital that you are prudent and work in partnership with your doctor. Can be taken alongside your existing medicationBecause the main ingredients are derived from foods, BreatheClear should have no negative interaction with any other medication or supplement. There are no reported cases of any problems of this nature. Try BreatheClear at our risk with this money-back guaranteeAs we have said, we can't guarantee that you will be one of the 50% that responds to BreatheClear. But we know that if you do benefit you are likely to become a long-term customer. So we think it makes sense to enable you to try BreatheClear at our risk, and find out if you do respond. If BreatheClear doesn't work out for you, just return the empty bottles and we will refund you promptly and courteously, no questions asked. So why not give BreatheClear a try, risk-free!
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Suitable for vegetarians & vegans
| Subjects | Average age |
Time on NT Factor |
Piper Fatigue Scale fatigue reduction |
Reference |
|---|---|---|---|---|
| Moderate/severe fatigue | 50.3 | 8 weeks | 33% | see paper |
| Moderate fatigue | 68.9 | 12 weeks | 32.3% (women) 42.9% (men) |
see paper |
| CFS/FMS | 44.8 | 8 weeks | 43.1% | see paper |
The study below was led by Prof Jerome B. Block MD of UCLA.
| Title | Content | Summary | Year | Reference |
|---|---|---|---|---|
| Results of a Study to Evaluate the Use of Propax to Reduce Adverse Effects of Chemotherapy | Clinical trial | Found that Propax with NT Factor is effective in reducing fatigue and many other side-effects of chemotherapy. | 2000 | see paper |
Other papers on Propax & NT Factor
| Title | Content | Summary | Year | Reference |
|---|---|---|---|---|
| Effects of Phosphoglycolipid Extract (NT Factor) on Normal and Cancerous Cells | Report | Pre-clinical work on the action of NT Factor | 1999 | see paper |
| Integration of Traditional and Complementary Medicine During Chemotherapy: A Physicians Viewpoint | Opinion | A physician's experience of using Propax to offset the side-effects of cancer treatment. | 2000 | see paper |
| Polyunsaturated Phosphatidylcholine in NT Factor Improves Mitochondrial Function, Auditory Sensitivity and May Slow Some of the Aging Processes | Animal Study | NT Factor may protect mitochondrial function by preserving the age-related decline in mitochondrial membrane potentials and reducing DNA damage | 2001 | see paper |
| Influence of Lecithin on Mitochondrial DNA and Age-related Hearing Loss (Abstract) | Animal Study | NT Factor may preserve cochlear mitochondrial function and protect from hearing loss associated with aging. | 2002 | see paper |
| Lipid Replacement as an Adjunct to Therapy for Chronic Fatigue, Anti-Aging and Restoration of Mitochondrial Function | Literature survey | Overview of the role of Lipid Replacement for treating fatigue. | 2003 | see paper |
| Lipid Replacement/Antioxidant Therapy as an Adjunct Supplement to Reduce the Adverse Effects of Cancer Therapy and Restore Mitochondrial Function* | Literature survey | A shorter survey of the role of Lipid Replacement in reducing the side-effects of chemotherapy. | 2005 | see paper |
| Molecular Replacement for Cancer Metabolic and Mitochondrial Dysfunction, Fatigue and the Adverse Effects of Cancer Therapy | Literature survey | Surveys literature on oxidative stress in cancer therapy and discusses the role of molecular replacement (Lipid Replacement Therapy) | 2006 | see paper |
| Metabolic Syndrome, Cardiovascular Disease and Mitochondrial Function: Molecular Replacement and Antioxidant Supplements to Prevent Membrane Oxidation and Restore Mitochondrial Function | Literature survey | Discussion of the role of Lipid Replacement Therapy in the treatment of Metabolic Syndrome | 2007 | see paper |
| Metabolic Syndrome and Mitochondrial Function: Molecular Replacement and Antioxidant Supplements to Prevent Membrane Peroxidation and Restore Mitochondrial Function | Literature survey | Role of Lipid Replacement Therapy in Metabolic disease. | 2007 | see paper |
| Reversing mitochondrial dysfunction, fatigue and the adverse effects of chemotherapy of metastatic disease by Molecular Replacement Therapy | Literature survey | The role of Lipid Replacement Therapy in mitigating the side-effects of chemotherapy. | 2007 | see paper |
| Diagnosis and Therapy of Chronic Systemic Co-infections in Lyme Disease and Other Tick-Borne Infectious Diseases | Literature survey | Role of Lipid Replacement Therapy in the treatment of Lyme Disease | 2007 | see paper |
| Molecular Replacement in Cancer Therapy: Reversing Cancer Metabolic and Mitochondrial Dysfunction, Fatigue and the Adverse Effects of Cancer Therapy | Literature survey | Detailed, up-to-date survey of oxidative stress in cancer therapy and the role of molecular replacement (Lipid Replacement Therapy) | 2008 | see paper |
Research evidence for Quercetin
Among the flavonoids, quercetin is possibly the most biologically active.
Quercetin is the aglycone (non-carbohydrate portion) of rutin, quercetrin and other glycoside flavonoids. It is widely distributed in the plant kingdom including oak trees (Quercus spp.), onions (Allium cepa) and tea (Camellia sinensis). It has effects on many different enzymatic systems in the body, most of them via its interaction with the calcium-regulating enzyme calmodulin (1).
Quercetin's effect on allergies is unmatched by other natural substances. It inhibits phospholipase A (responsible for converting phospholipids into arachidonic acid), lipoxygenase (responsible for converting arachidonic acid into leukotrienes)(2), platelet aggregation, and mast cell and basophil degranulation (3,4).
Quercetin has been shown to bind to calcium/calmodulin complexes, preventing the influx of calcium into mast cells and basophils (3,6). This inhibition prevents the mast cells from destabilizing and degranulating, keeping histamine and other preformed mediators from being released (7). In fact, quercetin so consistently blocks calcium induced mast cells destabilization that researchers often use it in experiments as a control substance for such activity (4,5).
Like most biologically active flavonoids, quercetin's pharmacology is quite interesting. The absorption of quercetin is about 20-52% depending on the form (8,9). While this may seem quite low, the elimination of quercetin and its derivatives is very low, and high plasma levels are easily maintained with a regular supply of quercetin in the diet (10). Studies conducted in rats showed that more than 25% of the absorbed quercetin was localized in the lung tissue, an added benefit to combat allergy and associated asthma (11).
Patients should begin to take quercetin upon the first signs of allergen exposure. Quercetin is prophylactic (stabilizing mast cells rather than blocking histamine) and will stay in the blood stream. Symptom relief may begin in the first several hours.
Quercetin is extremely safe, and has so many other benefits (antioxidant, anti-inflammatory, capillary stability etc.) it can help in the foundation of any natural approach to allergic rhinitis therapy.
REFERENCES
- Nishino, H. et.al. Quercetin interacts with Calmodulin, a calcium regulatory protein. Experientia 1984; 40:184-5.
- Yoshimoto, T. et.al. Flavonoids: Potent inhibitors of arachindonate 5-lipoxygenase. Biochem Biophys Res Com, 1983; 116:612-618.
- Middleton, E. et.al. Quercetin: An inhibitor of antigen-induced human basophil histamine release. Journal of Immunology, 1981; 127(2):546-550.
- Otsuka, H. et.al. Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: studies of nasal scrapings and their dispersed cells. J. Allergy Clin Immunol, 1995; 96(4):538-536.
- Szabo, A. et.al. Mucosal permeability changes during intestinal reperfusion injury. The role of mast cells. Acta Chir Hung, 1997; 36(1-4): 334-336.
- Fewtrell, C.M. and B.D. Gomperts. Quercetin: a novel inhibitor of Ca2+ influx and exocytosis in rat peritoneal mast cells. Biochim Biophys Acta, 1977; 469(1): 52-60.
- Leung, K.B., et.al. Differential effects of anti-allergic compounds on peritoneal mast cells of the rat, mouse and hamster. Agents Actions, 1984;14(3-4): 461-467.
- Hollman, P.C., et.al. Bioavailability of the dietary antioxidant flavonol quercetin in man. Cancer Lett, 1997;114(1-2): 139-140.
- Hollman, P.C. and M.B. Katan. Bioavailability and health effects of dietary flavonols in man. Arch Toxicol Suppl, 1998;20: 237-248.
- Manach, C. et.al. Bioavalability of rutin and quercetin in rats. FEBS Lett. 1997; 409(1): 12-16.
- Petrakis, P.L. et.al. Metabolic studies of quercetin labeled with 14 C. Arch. Biochem Biophys. 1959; 85:264-7.
Ingredients
Supplement Facts
Ingredient Amount %DV
Amino Acids ( L-Glycine, L-Taurine, L-Arginine) 400 mg *
Bioflavonoids ( Citrus, Quercetin, Rutin) 50 mg *
NT Factor (includes phosphoglycolipids derived from soy) 600 mg *
Other Ingredients: Microcrystalline cellulose, food glaze, croscarmellose sodium, vegetable magnesium stearate, silica.
*Daily value not established
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